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Rabbit anti-Human IRF2BP2 Polyclonal Antibody

The antibody against IRF2BP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 475-545 of human IRF2BP2 (Q7Z5L9) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07187A

The antibody against IRF2BP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 475-545 of human IRF2BP2 (Q7Z5L9) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-07187A ClonalityPolyclonal
Host SpeciesRabbitTarget NameIRF2BP2
Target SynonymsCVID14; IRF2BP2FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse lung, Mouse spleenApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 475-545 of human IRF2BP2 (Q7Z5L9).Target SpeciesHuman
Immunogen SequenceGGQGAGNTGGLEPVHPASLPDSSLATSAPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGUniprot IDQ7Z5L9
Background Information
  • Uniprot Id

    Q7Z5L9

  • Target Species

    Human

  • Target Name

    IRF2BP2

  • Target Full Name

    Interferon regulatory factor 2-binding protein 2

  • Target Function

    Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. Represses the NFAT1-dependent transactivation of NFAT-responsive promoters. Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles. Plays a role in immature B-cell differentiation.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    IRF2BP family

  • Target Synonyms

    I2BP2_HUMAN; Interferon regulatory factor 2 binding protein 2; Interferon regulatory factor 2-binding protein 2; IRF-2-binding protein 2; IRF-2BP2; IRF2 binding protein 2; IRF2BP2

  • Target Background

    This gene encodes an interferon regulatory factor-2 (IRF2) binding protein that interacts with the C-terminal transcriptional repression domain of IRF2. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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