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The antibody against ROS1 was raised in rabbit using the Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against ROS1 was raised in rabbit using the Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-11593A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ROS1 |
| Form | Liquid | Species Reactivity | Arabidopsis thaliana |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA) | Target Species | Arabidopsis thaliana (Mouse-ear cress) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9SJQ6 |
Uniprot Id
Q9SJQ6
Target Species
Arabidopsis thaliana
Target Name
ROS1
Target Function
Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity. Generates 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate. Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair.
Target Subcellular Location
Nucleus. Nucleus, nucleolus.
Target Protein Families
DNA glycosylase family, DEMETER subfamily
Target Tissue Specificity
Expressed ubiquitously in both vegetative and reproductive organs.
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