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Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ROS1 Polyclonal Antibody

The antibody against ROS1 was raised in rabbit using the Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-11593A

The antibody against ROS1 was raised in rabbit using the Recombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-11593A ClonalityPolyclonal
Host SpeciesRabbitTarget NameROS1
FormLiquidSpecies ReactivityArabidopsis thaliana
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Arabidopsis thaliana Protein ROS1 protein (1-320AA)Target SpeciesArabidopsis thaliana (Mouse-ear cress)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9SJQ6
Background Information
  • Uniprot Id

    Q9SJQ6

  • Target Species

    Arabidopsis thaliana

  • Target Name

    ROS1

  • Target Function

    Bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5-meC) and 5-hydroxymethylcytosine (5-hmeC), leaving an apyrimidinic (AP) site that is subsequently incised by the lyase activity. Generates 3'-phosphor-alpha,beta-unsaturated aldehyde (3'-PUA) as a primary 5-meC excision intermediate. Prevents DNA hypermethylation, specifically in the promoter of otherwise silenced loci. May be involved in DNA repair through its nicking activity on methylated DNA. Binds with similar affinity to both methylated and non-methylated DNA. Highly distributive behavior on DNA substrates containing multiple 5-meC residues. Involved with Pol IV in the remodeling of the 5S rDNA chromatin via DNA methylation modifications during the first days of development post-germination. Participates in UV-B induced- and oxidative DNA damage repair.

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus.

  • Target Protein Families

    DNA glycosylase family, DEMETER subfamily

  • Target Tissue Specificity

    Expressed ubiquitously in both vegetative and reproductive organs.

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