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The antibody against ANG1 was raised in rabbit using the Recombinant Bovine Angiogenin-1 protein (24-148AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against ANG1 was raised in rabbit using the Recombinant Bovine Angiogenin-1 protein (24-148AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-46387A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ANG1 |
| Target Synonyms | ANG1 antibody; ANGAngiogenin-1 antibody; EC 3.1.27.- antibody | Form | Liquid |
| Species Reactivity | Bovine | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Bovine Angiogenin-1 protein (24-148AA) | Target Species | Bos taurus (Bovine) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P10152 |
Uniprot Id
P10152
Target Species
Bovine
Target Name
ANG1
Target Function
Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. Has very low ribonuclease activity.
Target Subcellular Location
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus.
Target Protein Families
Pancreatic ribonuclease family
Target Tissue Specificity
Serum and milk.
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