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Rabbit anti-Hepatitis E virus genotype 1 ORF2 Polyclonal Antibody

The antibody against ORF2 was raised in rabbit using the Recombinant Hepatitis E virus genotype 1 Secreted protein ORF2 protein (20-660AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-44962A

The antibody against ORF2 was raised in rabbit using the Recombinant Hepatitis E virus genotype 1 Secreted protein ORF2 protein (20-660AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-44962A ClonalityPolyclonal
Host SpeciesRabbitTarget NameORF2
Target SynonymsORF2Secreted protein ORF2 antibody; Protein ORF2 antibody; pORF2 antibodyFormLiquid
Species ReactivityHepatitis E virus genotype 1IsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Hepatitis E virus genotype 1 Secreted protein ORF2 protein (20-660AA)Target SpeciesHepatitis E virus genotype 1
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ68985
Background Information
  • Uniprot Id

    Q68985

  • Target Species

    Hepatitis E virus genotype 1

  • Target Name

    ORF2

  • Target Function

    Plays a role in the inhibition of host antibody-mediated neutralization without blocking viral cell entry.; Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter. The capsid is composed of 60 copies linked to each other. Binds to the 5' end of the genomic RNA to mediate genome encapsidation. Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry. Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes.

  • Target Subcellular Location

    [Isoform Secreted protein ORF2]: Secreted.; [Isoform Capsid protein ORF2]: Virion. Host cytoplasm. Host endoplasmic reticulum. Host Golgi apparatus. Host cell surface.

  • Target Protein Families

    Hepevirus capsid protein family

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