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Rabbit anti-Human ACOT2 Polyclonal Antibody

The antibody against ACOT2 was raised in rabbit using the Human ACOT2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-54214A

The antibody against ACOT2 was raised in rabbit using the Human ACOT2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-54214A ClonalityPolyclonal
Host SpeciesRabbitTarget NameACOT2
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman ACOT2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP49753
Background Information
  • Uniprot Id

    P49753

  • Target Species

    Human

  • Target Name

    ACOT2

  • Target Full Name

    Acyl-coenzyme A thioesterase 2, mitochondrial

  • Target Function

    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. Displays higher activity toward long chain acyl CoAs (C14-C20). The enzyme is involved in enhancing the hepatic fatty acid oxidation in mitochondria.

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    C/M/P thioester hydrolase family

  • Target Tissue Specificity

    Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.

  • Target Synonyms

    ACOT2; PTE2; PTE2AAcyl-coenzyme A thioesterase 2; mitochondrial; Acyl-CoA thioesterase 2; EC 3.1.2.2; Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128

  • Target Background

    This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants.

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