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Rabbit anti-Human AP3S2 Polyclonal Antibody

The antibody against AP3S2 was raised in rabbit using the Recombinant Human AP-3 complex subunit sigma-2 protein (1-193AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-25260A

The antibody against AP3S2 was raised in rabbit using the Recombinant Human AP-3 complex subunit sigma-2 protein (1-193AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-25260A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAP3S2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human AP-3 complex subunit sigma-2 protein (1-193AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP59780
Background Information
  • Uniprot Id

    P59780

  • Target Species

    Human

  • Target Name

    AP3S2

  • Target Full Name

    AP-3 complex subunit sigma-2

  • Target Function

    Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

  • Target Subcellular Location

    Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.

  • Target Protein Families

    Adaptor complexes small subunit family

  • Target Tissue Specificity

    Present in all adult tissues examined.

  • Target Synonyms

    Adapter related protein complex 3 sigma 2 subunit; Adapter-related protein complex 3 sigma-2 subunit; AP 3 complex sigma 3B subunit; AP-3 complex subunit sigma-2; AP-3 complex subunit sigma-3B; Ap3s2; AP3S2_HUMAN; Clathrin adaptor complex AP3 sigma 3b subunit; Clathrin associated/assembly/adaptor protein; small 4 22-kD; Sigma 3B adaptin; Sigma adaptin 3b; Sigma-3B-adaptin; Sigma-adaptin 3b; Sigma3B-adaptin

  • Target Background

    Predicted to be involved in anterograde synaptic vesicle transport and vesicle-mediated transport. Located in intracellular membrane-bounded organelle. Part of AP-3 adaptor complex.

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