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The antibody against APCS was raised in rabbit using the Recombinant Human Serum amyloid P-component protein (20-223AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against APCS was raised in rabbit using the Recombinant Human Serum amyloid P-component protein (20-223AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-01727A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | APCS |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Serum amyloid P-component protein (20-223AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P02743 |
Uniprot Id
P02743
Target Species
Human
Target Name
APCS
Target Full Name
Serum amyloid P-component
Target Function
Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
Target Involvement
SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
Target Subcellular Location
Secreted.
Target Protein Families
Pentraxin family
Target Tissue Specificity
Found in serum and urine.
Target Research Area
Cardiovascular
Target Synonyms
9.5S alpha 1 glycoprotein; 9.5S alpha-1-glycoprotein; Amyloid P component serum; APCS; MGC88159; Pentaxin related; Pentraxin 2; PTX 2; PTX2; SAMP_HUMAN; SAP; Serum Amyloid P; Serum amyloid P component; Serum amyloid P-component(1-203)
Target Background
The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
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