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The antibody against ARFIP2 was raised in rabbit using the Recombinant Human Arfaptin-2 protein (20-295AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ARFIP2 was raised in rabbit using the Recombinant Human Arfaptin-2 protein (20-295AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human breast cancer using ARFIP2 Antibody at dilution of 1:1002
| Cat.No | ADC-25249A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARFIP2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Arfaptin-2 protein (20-295AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P53365 |
Uniprot Id
P53365
Target Species
Human
Target Name
ARFIP2
Target Full Name
Arfaptin-2
Target Function
Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network. May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2. Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site. In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.
Target Subcellular Location
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
Target Synonyms
ADP ribosylation factor interacting protein 2; ADP-ribosylation factor-interacting protein 2; Arfaptin 2; Arfaptin-2; ARFIP2; ARFP2_HUMAN; FLJ18046; FLJ18697; FLJ99239; Partner of RAC1; POR1; Protein POR1
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