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The antibody against ARHGAP1 was raised in rabbit using the Recombinant Human Rho GTPase-activating protein 1 protein (216-308AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ARHGAP1 was raised in rabbit using the Recombinant Human Rho GTPase-activating protein 1 protein (216-308AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using ARHGAP1 Antibody at dilution of 1:1002
| Cat.No | ADC-08237A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARHGAP1 |
| Target Synonyms | Rho | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Rho GTPase-activating protein 1 protein (216-308AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q07960 |
Uniprot Id
Q07960
Target Species
Human
Target Name
ARHGAP1
Target Full Name
Rho GTPase-activating protein 1
Target Function
GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
RHOGAP; RHOGAP1; CDC42GAP; p50rhoGAP; ARHGAP1
Target Background
This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members.
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