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The antibody against ASL was raised in rabbit using the Recombinant Human Argininosuccinate lyase protein (2-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ASL was raised in rabbit using the Recombinant Human Argininosuccinate lyase protein (2-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human liver cancer using ASL Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver tissue using ASL Antibody at dilution of 1:1002
| Cat.No | ADC-22217A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASL |
| Target Synonyms | Argininosuccinase antibody; Argininosuccinate lyase antibody; Arginosuccinase antibody; ARLY_HUMAN antibody; ASAL antibody; ASL antibody; EC 4.3.2.1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Argininosuccinate lyase protein (2-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P04424 |
Uniprot Id
P04424
Target Species
Human
Target Name
ASL
Target Full Name
Argininosuccinate lyase
Target Involvement
Argininosuccinic aciduria (ARGINSA)
Target Protein Families
Lyase 1 family, Argininosuccinate lyase subfamily
Target Synonyms
Argininosuccinase; Argininosuccinate lyase; Arginosuccinase; ARLY_HUMAN; ASAL; ASL; EC 4.3.2.1
Target Background
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
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