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Rabbit anti-Human BATF3 Polyclonal Antibody

The antibody against BATF3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human BATF3. as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-13124A

The antibody against BATF3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human BATF3. as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-13124A ClonalityPolyclonal
Host SpeciesRabbitTarget NameBATF3
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human BATF3.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NR55
Background Information
  • Uniprot Id

    Q9NR55

  • Target Species

    Human

  • Target Name

    BATF3

  • Target Full Name

    Basic leucine zipper transcriptional factor ATF-like 3

  • Target Function

    AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    BZIP family

  • Target Synonyms

    BATF3; SNFTBasic leucine zipper transcriptional factor ATF-like 3; B-ATF-3; 21 kDa small nuclear factor isolated from T-cells; Jun dimerization protein p21SNFT

  • Target Background

    This gene encodes a member of the basic leucine zipper protein family. The encoded protein functions as a transcriptional repressor when heterodimerizing with JUN. The protein may play a role in repression of interleukin-2 and matrix metalloproteinase-1 transcription.

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