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The antibody against BLVRB was raised in rabbit using the Recombinant Human Flavin reductase (NADPH) protein (2-206AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against BLVRB was raised in rabbit using the Recombinant Human Flavin reductase (NADPH) protein (2-206AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Western Blot | Positive WB detected in: K562 whole cell lysate, PC3 whole cell lysate, HepG2 whole cell lysate | All lanes: BLVRB antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 23 kDa | Observed band size: 23 kDa
| Cat.No | ADC-01725A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BLVRB |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Flavin reductase (NADPH) protein (2-206AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P30043 |
Uniprot Id
P30043
Target Species
Human
Target Name
BLVRB
Target Full Name
Flavin reductase (NADPH)
Target Function
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.
Target Synonyms
Biliverdin IX beta reductase; biliverdin reductase B (flavin reductase (NADPH)); Biliverdin reductase B; Biliverdin-IX beta-reductase; BLVRB; BLVRB_HUMAN; BVR B; BVR-B; BVRB; epididymis secretory protein Li 10; Flavin reductase (NADPH); Flavin reductase; FLR; FR; GHBP; Green heme binding protein; Green heme-binding protein; HEL-S-10; Methemoglobin reductase; MGC117413; NADPH dependent diaphorase; NADPH flavin reductase; NADPH-dependent diaphorase; NADPH-flavin reductase; SDR43U1; short chain dehydrogenase/reductase family 43U; member 1
Target Background
Enables biliverdin reductase (NAD(P)+) activity and riboflavin reductase (NADPH) activity. Involved in heme catabolic process. Located in cytosol; nucleoplasm; and plasma membrane.
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