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The antibody against BST1 was raised in rabbit using the Synthesized peptide derived from internal of Human BST1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against BST1 was raised in rabbit using the Synthesized peptide derived from internal of Human BST1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from Jurkat cells and COS cells, using BST1 antibody.
| Cat.No | ADC-41512A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BST1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human BST1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q10588 |
Uniprot Id
Q10588
Target Species
Human
Target Name
BST1
Target Full Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
Target Function
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
ADP-ribosyl cyclase family
Target Tissue Specificity
Widely expressed.
Target Synonyms
ADP ribosyl cyclase 2; ADP-ribosyl cyclase 2; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2; Bone marrow stromal antigen 1; Bone marrow stromal cell antigen 1; BST 1; BST-1; BST1; BST1_HUMAN; cADPr hydrolase 2; CD157; CD157 antigen; Cyclic ADP ribose hydrolase 2; Cyclic ADP-ribose hydrolase 2; NAD(+) nucleosidase; OTTHUMP00000217617
Target Background
Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
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