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Rabbit anti-Human BTG1 Polyclonal Antibody

The antibody against BTG1 was raised in rabbit using the Fusion protein of Human BTG1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-32224A

The antibody against BTG1 was raised in rabbit using the Fusion protein of Human BTG1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-32224A ClonalityPolyclonal
Host SpeciesRabbitTarget NameBTG1
Target SynonymsBTG1Protein BTG1 antibody; B-cell translocation gene 1 protein antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBSPurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human BTG1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP62324
Background Information
  • Uniprot Id

    P62324

  • Target Species

    Human

  • Target Name

    BTG1

  • Target Full Name

    Protein BTG1

  • Target Function

    Anti-proliferative protein.

  • Target Involvement

    A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC.

  • Target Protein Families

    BTG family

  • Target Synonyms

    BTG1Protein BTG1; B-cell translocation gene 1 protein

  • Target Background

    This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.

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