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Rabbit anti-Human BTN3A3 Polyclonal Antibody

The antibody against BTN3A3 was raised in rabbit using the Recombinant Human Butyrophilin subfamily 3 member A3 protein (30-248AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-25205A

The antibody against BTN3A3 was raised in rabbit using the Recombinant Human Butyrophilin subfamily 3 member A3 protein (30-248AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-25205A ClonalityPolyclonal
Host SpeciesRabbitTarget NameBTN3A3
Target SynonymsBT3A3_HUMAN antibody; BTF3 antibody; BTN3A3 antibody; Butyrophilin subfamily 3 member A3 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Butyrophilin subfamily 3 member A3 protein (30-248AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO00478
Background Information
  • Uniprot Id

    O00478

  • Target Species

    Human

  • Target Name

    BTN3A3

  • Target Full Name

    Butyrophilin subfamily 3 member A3

  • Target Function

    Plays a role in T-cell responses in the adaptive immune response.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Immunoglobulin superfamily, BTN/MOG family

  • Target Tissue Specificity

    Detected in peripheral blood mononuclear cells and in T-cells (at protein level). Detected in spleen and lymphocytes.

  • Target Research Area

    Cardiovascular

  • Target Synonyms

    BT3A3_HUMAN; BTF3; BTN3A3; Butyrophilin subfamily 3 member A3

  • Target Background

    The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).

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