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Rabbit anti-Human C6 Polyclonal Antibody

The antibody against C6 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human C6. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-39184A

The antibody against C6 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human C6. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-39184A ClonalityPolyclonal
Host SpeciesRabbitTarget NameC6
Target SynonymsAW111623 antibody; C6 antibody; CO6_HUMAN antibody; Complement component 6 antibody; Complement component C6 antibodyFormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human C6.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP13671
Background Information
  • Uniprot Id

    P13671

  • Target Species

    Human

  • Target Name

    C6

  • Target Full Name

    Complement component C6

  • Target Function

    Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.

  • Target Involvement

    Complement component 6 deficiency (C6D)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Complement C6/C7/C8/C9 family

  • Target Synonyms

    AW111623; C6; CO6_HUMAN; Complement component 6; Complement component C6

  • Target Background

    This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.

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