Rabbit anti-Human CD134/OX40 Polyclonal Antibody

The antibody against CD134/OX40 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD134/OX40 (NP_003318.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04089A

Number

Cat.No	ADA-04089A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CD134/OX40
Target Synonyms	OX40; ACT35; CD134; IMD16; TXGP1L; CD134/OX40	Form	Liquid
Species Reactivity	Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat liver	Application	ELISA, WB

Cat.No

ADA-04089A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CD134/OX40

Target Synonyms

OX40; ACT35; CD134; IMD16; TXGP1L; CD134/OX40

Form

Liquid

Species Reactivity

Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat liver

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD134/OX40 (NP_003318.1).	Target Species	Human
Immunogen Sequence	TATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQGPPARPITVQPTEAWPRTSQ	Uniprot ID	P43489

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CD134/OX40 (NP_003318.1).

Target Species

Human

Immunogen Sequence

TATQDTVCRCRAGTQPLDSYKPGVDCAPCPPGHFSPGDNQACKPWTNCTLAGKHTLQPASNSSDAICEDRDPPATQPQETQGPPARPITVQPTEAWPRTSQ

Uniprot ID

P43489

Background Information

Uniprot Id

P43489
Target Species

Human
Target Name

TNFRSF4
Target Full Name

Tumor necrosis factor receptor superfamily member 4
Target Function

Receptor for TNFSF4/OX40L/GP34. Is a costimulatory molecule implicated in long-term T-cell immunity.; (Microbial infection) Acts as a receptor for human herpesvirus 6B/HHV-6B.
Target Involvement

Immunodeficiency 16 (IMD16)
Target Subcellular Location

Membrane; Single-pass type I membrane protein.
Target Research Area

Immunology
Target Synonyms

TNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD antigen CD134
Target Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

Rabbit anti-Human CD134/OX40 Polyclonal Antibody

Specifications

Immunogen Information

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