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Rabbit anti-Human CHI3L2 Polyclonal Antibody

The antibody against CHI3L2 was raised in rabbit using the Recombinant Human Chitinase-3-like protein 2 protein (27-390AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-49408A

The antibody against CHI3L2 was raised in rabbit using the Recombinant Human Chitinase-3-like protein 2 protein (27-390AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-49408A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCHI3L2
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Chitinase-3-like protein 2 protein (27-390AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ15782
Background Information
  • Uniprot Id

    Q15782

  • Target Species

    Human

  • Target Name

    CHI3L2

  • Target Full Name

    Chitinase-3-like protein 2

  • Target Function

    Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Glycosyl hydrolase 18 family

  • Target Tissue Specificity

    Highest expression in chondrocytes, followed by synoviocytes, lung and heart. Not detected in spleen, pancreas, and liver. May also be expressed in developing brain and placenta.

  • Target Synonyms

    CH3L2_HUMAN; CHI3L2; Chitinase 3 like 2; Chitinase-3-like protein 2; Chondrocyte protein 39; OTTHUMP00000014028; YKL 39; YKL-39; YKL39

  • Target Background

    The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene.

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