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The antibody against CHRD was raised in rabbit using the Synthetic peptide from Human protein at AA range: 905-954 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against CHRD was raised in rabbit using the Synthetic peptide from Human protein at AA range: 905-954 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:200
Immunohistochemical analysis of paraffin-embedded human-liver-cancer, antibody was diluted at 1:2002
| Cat.No | ADC-12971A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHRD |
| Target Synonyms | CHRD antibody; UNQ217/PRO243Chordin antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS |
| Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 905-954 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H2X0 |
Uniprot Id
Q9H2X0
Target Species
Human
Target Name
CHRD
Target Full Name
Chordin
Target Function
Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes.
Target Subcellular Location
Secreted.
Target Protein Families
Chordin family
Target Tissue Specificity
Expressed at the highest level in liver.
Target Synonyms
CHRD; UNQ217/PRO243Chordin
Target Background
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. It has been suggested that this gene could be a candidate gene for Cornelia de Lange syndrome. Reduced expression of this gene results in enhanced bone regeneration. Alternative splicing results in multiple transcript variants. Other alternative splice variants have been described but their full length sequence has not been determined.
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