Rabbit anti-Human CLC Polyclonal Antibody

The antibody against CLC was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human CLC (NP_001819.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05177A

Number

Cat.No	ADA-05177A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CLC
Target Synonyms	GAL10; Gal-10; LGALS10; LGALS10A; LPPL_HUMAN; CLC	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HepG2, HL-60	Application	ELISA, WB

Cat.No

ADA-05177A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CLC

Target Synonyms

GAL10; Gal-10; LGALS10; LGALS10A; LPPL_HUMAN; CLC

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HepG2, HL-60

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human CLC (NP_001819.2).	Target Species	Human
Immunogen Sequence	MSLLPVPYTEAASLSTGSTVTIKGRPLACFLNEPYLQVDFHTEMKEESDIVFHFQVCFGRRVVMNSREYGAWKQQVESKNMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSYLKR	Uniprot ID	Q05315

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human CLC (NP_001819.2).

Target Species

Human

Immunogen Sequence

MSLLPVPYTEAASLSTGSTVTIKGRPLACFLNEPYLQVDFHTEMKEESDIVFHFQVCFGRRVVMNSREYGAWKQQVESKNMPFQDGQEFELSISVLPDKYQVMVNGQSSYTFDHRIKPEAVKMVQVWRDISLTKFNVSYLKR

Uniprot ID

Q05315

Background Information

Uniprot Id

Q05315
Target Species

Human
Target Name

CLC
Target Full Name

Galectin-10
Target Function

Regulates immune responses through the recognition of cell-surface glycans. Essential for the anergy and suppressive function of CD25-positive regulatory T-cells (Treg).
Target Subcellular Location

Cytoplasm, cytosol. Cytoplasmic granule. Note=Localized in granules from where it may be secreted or transported to other locations in the cell.
Target Tissue Specificity

Expressed abundantly in the bone marrow. Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils. Expressed in CD25-positive regulatory T-cells (Treg) (at protein level). Found in intestinal tissue from patients with
Target Synonyms

GAL10; Gal-10; LGALS10; LGALS10A; LPPL_HUMAN; CLC
Target Background

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. The protein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzes lysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate or IgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactoside binding proteins. It may be associated with inflammation and some myeloid leukemias.

Rabbit anti-Human CLC Polyclonal Antibody

Specifications

Immunogen Information

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