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The antibody against CLSTN3 was raised in rabbit using the Recombinant Human Calsyntenin-3 protein (197-408AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IF.
The antibody against CLSTN3 was raised in rabbit using the Recombinant Human Calsyntenin-3 protein (197-408AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-00777A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CLSTN3 |
| Target Synonyms | CLSTN3 antibody; CS3 antibody; KIAA0726Calsyntenin-3 antibody; Alcadein-beta antibody; Alc-beta antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Calsyntenin-3 protein (197-408AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BQT9 |
Uniprot Id
Q9BQT9
Target Species
Human
Target Name
CLSTN3
Target Full Name
Calsyntenin-3
Target Function
May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell junction, synapse, postsynapse. Cell projection, dendrite.
Target Tissue Specificity
According to PubMed:12498782, expressed predominantly in the brain and in kidney. Low levels in heart, skeletal muscle, liver, placenta, pancreas and lung. According to PubMed:12972431, predominant expression in brain, and only marginal in kidney. In brai
Target Synonyms
CLSTN3; CS3; KIAA0726Calsyntenin-3; Alcadein-beta; Alc-beta
Target Background
Predicted to enable calcium ion binding activity. Predicted to be involved in positive regulation of synapse assembly and positive regulation of synaptic transmission. Predicted to act upstream of or within several processes, including chemical synaptic transmission; positive regulation of protein localization to synapse; and synapse assembly. Predicted to be located in postsynaptic density. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynaptic membrane. Predicted to be integral component of postsynaptic density membrane.
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