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The antibody against CNDP2 was raised in rabbit using the Recombinant Human Cytosolic non-specific dipeptidase protein (2-475AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CNDP2 was raised in rabbit using the Recombinant Human Cytosolic non-specific dipeptidase protein (2-475AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human endometrial cancer using CNDP2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human prostate cancer using CNDP2 Antibody at dilution of 1:1002
| Cat.No | ADC-50241A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CNDP2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cytosolic non-specific dipeptidase protein (2-475AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96KP4 |
Uniprot Id
Q96KP4
Target Species
Human
Target Name
CNDP2
Target Full Name
Cytosolic non-specific dipeptidase
Target Function
Catalyzes the peptide bond hydrolysis in dipeptides, displaying a non-redundant activity toward threonyl dipeptides. Mediates threonyl dipeptide catabolism in a tissue-specific way. Has high dipeptidase activity toward cysteinylglycine, an intermediate metabolite in glutathione metabolism. Metabolizes N-lactoyl-amino acids, both through hydrolysis to form lactic acid and amino acids, as well as through their formation by reverse proteolysis. Plays a role in the regulation of cell cycle arrest and apoptosis.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Peptidase M20A family
Target Tissue Specificity
[Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes. Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level).; [Isoform 2]: Bro
Target Research Area
Cell Biology
Target Synonyms
0610010E05Rik; C76600; Carnosinase ; tissue; Carnosinase 2; CN 2; CN2; CNDP 2; CNDP dipeptidase 2 (metallopeptidase M20 family); CNDP dipeptidase 2; CNDP2; CNDP2_HUMAN; CPGL; Cytosolic non specific dipeptidase; Cytosolic non-specific dipeptidase; Cytosolic nonspecific dipeptidase; Dip-2; FLJ10830; FLJ35544; Glutamate carboxypeptidase like protein 1; Glutamate carboxypeptidase-like protein 1; HsT2298; Nonspecific dipeptidase; cutosolic; Pep-1; Pep1; PEPA; Peptidase A
Target Background
CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).
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