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Rabbit anti-Human CNTN2 Polyclonal Antibody

The antibody against CNTN2 was raised in rabbit using the Synthesized peptide derived from internal of Human CNTN2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41298A

The antibody against CNTN2 was raised in rabbit using the Synthesized peptide derived from internal of Human CNTN2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41298A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCNTN2
FormLiquidSpecies ReactivityHuman
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human CNTN2.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ02246
Background Information
  • Uniprot Id

    Q02246

  • Target Species

    Human

  • Target Name

    CNTN2

  • Target Full Name

    Contactin-2

  • Target Function

    In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region. May be involved in cell adhesion.

  • Target Involvement

    Epilepsy, familial adult myoclonic, 5 (FAME5)

  • Target Subcellular Location

    Cell membrane; Lipid-anchor, GPI-anchor. Note=Attached to the neuronal membrane by a GPI-anchor and is also released from neurons.

  • Target Protein Families

    Immunoglobulin superfamily, Contactin family

  • Target Synonyms

    AXT; TAX; TAX1; FAME5; TAG-1; Contactin 2

  • Target Background

    This gene encodes a member of the contactin family of proteins, part of the immunoglobulin superfamily of cell adhesion molecules. The encoded glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein plays a role in the proliferation, migration, and axon guidance of neurons of the developing cerebellum. A mutation in this gene may be associated with adult myoclonic epilepsy.

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