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The antibody against COIL was raised in rabbit using the Recombinant Human Coilin protein (297-576AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against COIL was raised in rabbit using the Recombinant Human Coilin protein (297-576AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-40257A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COIL |
| Target Synonyms | CLN 80 antibody; CLN80 antibody; COIL antibody; COIL_HUMAN antibody; Coilin antibody; Coilin p80 antibody; p80 antibody; P80 coilin antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Coilin protein (297-576AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P38432 |
Uniprot Id
P38432
Target Species
Human
Target Name
COIL
Target Full Name
Coilin
Target Function
Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
Target Subcellular Location
Nucleus. Nucleus, Cajal body.
Target Protein Families
Coilin family
Target Tissue Specificity
Found in all the cell types examined.
Target Synonyms
CLN 80; CLN80; COIL; COIL_HUMAN; Coilin; Coilin p80; p80; P80 coilin
Target Background
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.
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