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Rabbit anti-Human CP Polyclonal Antibody

The antibody against CP was raised in rabbit using the Recombinant Human Ceruloplasmin protein (807-1050AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-46416A

The antibody against CP was raised in rabbit using the Recombinant Human Ceruloplasmin protein (807-1050AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-46416A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCP
Target SynonymsCERU_HUMAN antibody; Ceruloplasmin antibody; CP 2 antibody; CP antibody; CP2 antibody; Ferroxidase antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Ceruloplasmin protein (807-1050AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP00450
Background Information
  • Uniprot Id

    P00450

  • Target Species

    Human

  • Target Name

    CP

  • Target Full Name

    Ceruloplasmin

  • Target Function

    Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense.

  • Target Involvement

    Aceruloplasminemia (ACERULOP)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Multicopper oxidase family

  • Target Tissue Specificity

    Expressed by the liver and secreted in plasma.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    CERU_HUMAN; Ceruloplasmin; CP 2; CP; CP2; Ferroxidase

  • Target Background

    The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

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