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Rabbit anti-Human CTSH Polyclonal Antibody

The antibody against CTSH was raised in rabbit using the Human CTSH as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-53662A

The antibody against CTSH was raised in rabbit using the Human CTSH as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-53662A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCTSH
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman CTSHTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP09668
Background Information
  • Uniprot Id

    P09668

  • Target Species

    Human

  • Target Name

    CTSH

  • Target Full Name

    Pro-cathepsin H

  • Target Function

    Important for the overall degradation of proteins in lysosomes.

  • Target Subcellular Location

    Lysosome.

  • Target Protein Families

    Peptidase C1 family

  • Target Synonyms

    ACC4; ACC5; CPSB; ACC-4; ACC-5; CTSH

  • Target Background

    The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.

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