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Rabbit anti-Human DDX46 Polyclonal Antibody

The antibody against DDX46 was raised in rabbit using the Human DDX46 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.

ADC-48775A

The antibody against DDX46 was raised in rabbit using the Human DDX46 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.

$600.00

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Specifications


Cat.No ADC-48775A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDDX46
Target SynonymsDDX46 antibody; KIAA0801Probable ATP-dependent RNA helicase DDX46 antibody; EC 3.6.4.13 antibody; DEAD box protein 46 antibody; PRP5 homolog antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IF, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman DDX46Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ7L014
Background Information
  • Uniprot Id

    Q7L014

  • Target Species

    Human

  • Target Name

    DDX46

  • Target Full Name

    Probable ATP-dependent RNA helicase DDX46

  • Target Function

    Plays an essential role in splicing, either prior to, or during splicing A complex formation.

  • Target Subcellular Location

    Nucleus speckle. Nucleus, Cajal body. Membrane; Lipid-anchor. Note=Present in Cajal bodies (CBs) and nuclear speckles.

  • Target Protein Families

    DEAD box helicase family, DDX46/PRP5 subfamily

  • Target Synonyms

    DDX46; KIAA0801Probable ATP-dependent RNA helicase DDX46; EC 3.6.4.13; DEAD box protein 46; PRP5 homolog

  • Target Background

    This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the 17S U2 snRNP complex; it plays an important role in pre-mRNA splicing. Multiple alternatively spliced transcript variants have been found for this gene.

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