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The antibody against DENND5A was raised in rabbit using the Recombinant Human DENN domain-containing protein 5A protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against DENND5A was raised in rabbit using the Recombinant Human DENN domain-containing protein 5A protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon tissue using DENND5A Antibody at dilution of 1:100
| Cat.No | ADC-19633A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DENND5A |
| Target Synonyms | DENND5A antibody; KIAA1091 antibody; RAB6IP1DENN domain-containing protein 5A antibody; Rab6-interacting protein 1 antibody; Rab6IP1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human DENN domain-containing protein 5A protein (1-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6IQ26 |
Uniprot Id
Q6IQ26
Target Species
Human
Target Name
DENND5A
Target Full Name
DENN domain-containing protein 5A
Target Function
Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth.
Target Involvement
Epileptic encephalopathy, early infantile, 49 (EIEE49)
Target Subcellular Location
Golgi apparatus membrane.
Target Protein Families
RAB6IP1 family
Target Synonyms
DENND5A; KIAA1091; RAB6IP1DENN domain-containing protein 5A; Rab6-interacting protein 1; Rab6IP1
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