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Rabbit anti-Human EIF4E3 Polyclonal Antibody

The antibody against EIF4E3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human EIF4E3 (NP_775495.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00687A

The antibody against EIF4E3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human EIF4E3 (NP_775495.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-00687A ClonalityPolyclonal
Host SpeciesRabbitTarget NameEIF4E3
Target SynonymseIF-4E3; eIF4E-3; EIF4E3FormLiquid
Species ReactivityMouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse lung, Rat lungApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-118 of human EIF4E3 (NP_775495.1).Target SpeciesHuman
Immunogen SequenceMRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEVIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIYELLPHITFKAVFYKPHEEHHAFEGGRGKHUniprot IDQ8N5X7
Background Information
  • Uniprot Id

    Q8N5X7

  • Target Species

    Human

  • Target Name

    EIF4E3

  • Target Full Name

    Eukaryotic translation initiation factor 4E type 3

  • Target Function

    Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis. May act as an inhibitor of EIF4E1 activity.

  • Target Protein Families

    Eukaryotic initiation factor 4E family

  • Target Synonyms

    EIF4E3Eukaryotic translation initiation factor 4E type 3; eIF-4E type 3; eIF-4E3; eIF4E type 3; eIF4E-3

  • Target Background

    EIF4E3 belongs to the EIF4E family of translational initiation factors that interact with the 5-prime cap structure of mRNA and recruit mRNA to the ribosome (Joshi et al., 2004 [PubMed 15153109]).

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