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The antibody against ELMOD3 was raised in rabbit using the Recombinant Human ELMO domain-containing protein 3 protein (1-102AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ELMOD3 was raised in rabbit using the Recombinant Human ELMO domain-containing protein 3 protein (1-102AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-05551A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ELMOD3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human ELMO domain-containing protein 3 protein (1-102AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96FG2 |
Uniprot Id
Q96FG2
Target Species
Human
Target Name
ELMOD3
Target Full Name
ELMO domain-containing protein 3
Target Function
Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity.
Target Involvement
Deafness, autosomal recessive, 88 (DFNB88)
Target Subcellular Location
Cell projection, stereocilium. Cell projection, kinocilium. Cytoplasm, cytoskeleton.
Target Tissue Specificity
Both isoform 1 and isoform 6 are widely expressed.
Target Synonyms
ELMOD3; RBED1; RBM29; PP4068ELMO domain-containing protein 3; RNA-binding motif and ELMO domain-containing protein 1; RNA-binding motif protein 29; RNA-binding protein 29
Target Background
This gene encodes a member of the engulfment and cell motility family of GTPase-activating proteins that regulate Arf GTPase proteins. Members of this family are defined by a conserved engulfment and cell motility domain. In rat cochlea, the encoded protein is found in stereocilia, kinocilia and cuticular plate of developing hair cells suggesting a function for this protein in cochlear sensory cells. An allelic variant of this family has been associated with autosomal recessive nonsyndromic deafness-88 in humans. Alternative splicing results in multiple transcript variants.
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