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The antibody against EMC6 was raised in rabbit using the Recombinant Human ER membrane protein complex subunit 6 protein (2-47AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against EMC6 was raised in rabbit using the Recombinant Human ER membrane protein complex subunit 6 protein (2-47AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human testis tissue using EMC6 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using EMC6 Antibody at dilution of 1:1002
Immunofluorescent analysis of MCF-7 cells using EMC6 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-24990A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EMC6 |
| Target Synonyms | EMC6; TMEM93; ER membrane protein complex subunit 6; Transmembrane protein 93 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human ER membrane protein complex subunit 6 protein (2-47AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BV81 |
Uniprot Id
Q9BV81
Target Species
Human
Target Name
EMC6
Target Full Name
ER membrane protein complex subunit 6
Target Function
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues. Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices. It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors. By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable).
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
EMC6 family
Target Synonyms
EMC6; TMEM93; ER membrane protein complex subunit 6; Transmembrane protein 93
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