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The antibody against EPG5 was raised in rabbit using the Recombinant Protein as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on WB, IHC.
The antibody against EPG5 was raised in rabbit using the Recombinant Protein as the immunogen. This antibody exists as a non-conjugated isotype IgG. This antibody has been validated on WB, IHC.
$167.00
Immunohistochemical analysis of paraffin-embedded Mouse Liver Tissue using EPG5 Polyclonal Antibody.
Western blot analysis of Rat Liver Tissue using EPG5 Polyclonal Antibody.2
| Cat.No | ADC-33142A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EPG5 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS |
| Conjugate | Non-conjugated | Application | IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HCE0 |
Uniprot Id
Q9HCE0
Target Species
Human
Target Name
EPG5
Target Full Name
Ectopic P granules protein 5 homolog
Target Function
Involved in autophagy. May play a role in a late step of autophagy, such as clearance of autophagosomal cargo. Plays a key role in innate and adaptive immune response triggered by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides from pathogens, and mediated by the nucleotide-sensing receptor TLR9. It is necessary for the translocation of CpG dinucleotides from early endosomes to late endosomes and lysosomes, where TLR9 is located.
Target Involvement
Vici syndrome (VICIS)
Target Subcellular Location
Cytoplasm, perinuclear region. Lysosome.
Target Protein Families
EPG5 family
Target Synonyms
Ectopic P granules autophagy protein 5 homolog (C. elegans); Ectopic P granules protein 5 homolog; Epg5; EPG5_HUMAN; HEEW1; hEPG5; KIAA1632
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