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Rabbit anti-Human EPS15L1 Polyclonal Antibody

The antibody against EPS15L1 was raised in rabbit using the Human EPS15L1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.

ADC-48631A

The antibody against EPS15L1 was raised in rabbit using the Human EPS15L1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.

$600.00

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Specifications


Cat.No ADC-48631A ClonalityPolyclonal
Host SpeciesRabbitTarget NameEPS15L1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman EPS15L1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UBC2
Background Information
  • Uniprot Id

    Q9UBC2

  • Target Species

    Human

  • Target Name

    EPS15L1

  • Target Full Name

    Epidermal growth factor receptor substrate 15-like 1

  • Target Function

    Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.

  • Target Subcellular Location

    Cell membrane; Peripheral membrane protein. Nucleus. Membrane, coated pit.

  • Target Synonyms

    EP15R_HUMAN; epidermal growth factor receptor pathway substrate 15- ike 1; Epidermal growth factor receptor substrate 15 like 1; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15 related protein; Eps15-related protein; EPS15L1; Eps15R

  • Target Background

    Enables cadherin binding activity. Predicted to be involved in endocytosis and endosomal transport. Located in membrane.

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