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The antibody against ERN2 was raised in rabbit using the Synthetic peptide of Human ERN2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ERN2 was raised in rabbit using the Synthetic peptide of Human ERN2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-26762A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ERN2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human ERN2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q76MJ5 |
Uniprot Id
Q76MJ5
Target Species
Human
Target Name
ERN2
Target Full Name
Serine/threonine-protein kinase/endoribonuclease IRE2
Target Function
Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Target Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Target Synonyms
ERN2; IRE2Serine/threonine-protein kinase/endoribonuclease IRE2; Endoplasmic reticulum-to-nucleus signaling 2; Inositol-requiring protein 2; hIRE2p; Ire1-beta; IRE1b) [Includes: Serine/threonine-protein kinase; EC 2.7.11.1); Endoribonuclease; EC 3.1.26.-)]
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