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The antibody against ETV7 was raised in rabbit using the Recombinant Human Transcription factor ETV7 protein (134-218AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ETV7 was raised in rabbit using the Recombinant Human Transcription factor ETV7 protein (134-218AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-11299A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ETV7 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription factor ETV7 protein (134-218AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y603 |
Uniprot Id
Q9Y603
Target Species
Human
Target Name
ETV7
Target Full Name
Transcription factor ETV7
Target Function
Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Tissue Specificity
Expressed in hematopoietic tissues.
Target Synonyms
ETS related protein Tel2; Ets transcription factor TEL-2b; Ets transcription factor TEL2; ETS translocation variant 7; ets variant 7; ets variant gene 7 (TEL2 oncogene); ets variant gene 7; ETS-related protein Tel2; ETV7; ETV7_HUMAN; TEL 2; Tel related Ets factor ; Tel-related Ets factor; TEL2 ; TEL2 oncogene; TELB; Transcription factor ETV7; Transcription factor Tel 2; Transcription factor Tel-2; TREF
Target Background
The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).
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