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The antibody against FILIP1L was raised in rabbit using the Recombinant Human Filamin A-interacting protein 1-like protein as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against FILIP1L was raised in rabbit using the Recombinant Human Filamin A-interacting protein 1-like protein as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using FILIP1L Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon tissue using FILIP1L Antibody at dilution of 1:1002
| Cat.No | ADC-24871A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FILIP1L |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Filamin A-interacting protein 1-like protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q4L180 |
Uniprot Id
Q4L180
Target Species
Human
Target Name
FILIP1L
Target Full Name
Filamin A-interacting protein 1-like
Target Function
Acts as a regulator of the antiangiogenic activity on endothelial cells. When overexpressed in endothelial cells, leads to inhibition of cell proliferation and migration and an increase in apoptosis. Inhibits melanoma growth When expressed in tumor-associated vasculature.
Target Subcellular Location
Cytoplasm. Membrane. Nucleus.
Target Protein Families
FILIP1 family
Target Tissue Specificity
Expressed in endothelial cells, colon and colon cancers. In the colon, expressed in the vasculature and muscularis mucosa. In colon cancer, strongly expressed in tumor stroma and the vasculature (at protein level). Expressed in ovarian epithelial cells. D
Target Research Area
Cancer
Target Synonyms
130 kDa GPBP-interacting protein; 90 kDa GPBP-interacting protein; COL4A3BPIP; DOC-1; DOC1; Downregulated in ovarian cancer 1 81 kDa isoform; FIL1L_HUMAN; Filamin A-interacting protein 1-like; FILIP1L; GIP130; GIP130a; GIP130b; GIP130c; GIP90; GPBP interacting protein 90; Protein down-regulated in ovarian cancer 1
Target Background
Predicted to be located in cytoplasm; membrane; and nucleus.
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