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Rabbit anti-Human FLI1 Polyclonal Antibody

The antibody against FLI1 was raised in rabbit using the Peptide sequence around aa.251~255(S-K-N-T-E)derived from Human FLI1. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.

ADC-43215A

The antibody against FLI1 was raised in rabbit using the Peptide sequence around aa.251~255(S-K-N-T-E)derived from Human FLI1. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-43215A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFLI1
FormLiquidSpecies ReactivityHuman
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionPeptide sequence around aa.251~255(S-K-N-T-E)derived from Human FLI1.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ01543
Background Information
  • Uniprot Id

    Q01543

  • Target Species

    Human

  • Target Name

    FLI1

  • Target Full Name

    Friend leukemia integration 1 transcription factor

  • Target Function

    Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.

  • Target Involvement

    Ewing sarcoma (ES); Bleeding disorder, platelet-type 21 (BDPLT21)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ETS family

  • Target Research Area

    Cancer

  • Target Synonyms

    (Proto-oncogene Fli-1)(Transcription factor ERGB)

  • Target Background

    This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

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