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Rabbit anti-Human FMNL1 Polyclonal Antibody

The antibody against FMNL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_005883.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03372A

The antibody against FMNL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_005883.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03372A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFMNL1
Target SynonymsFMNL; FHOD4; KW-13; C17orf1; C17orf1B; FMNL1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesA-549, LO2, Mouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 900-1070 of human FMNL1 (NP_005883.2).Target SpeciesHuman
Immunogen SequenceDLHFLDKAGSVSLDSVLADVRSLQRGLELTQREFVRQDDCMVLKEFLRANSPTMDKLLADSKTAQEAFESVVEYFGENPKTTSPGLFFSLFSRFIKAYKKAEQEVEQWKKEAAAQEAGADTPGKGEPPAPKSPPKARRPQMDLISELKRRQQKEPLIYESDRDGAIEDIITUniprot IDO95466
Background Information
  • Uniprot Id

    O95466

  • Target Species

    Human

  • Target Name

    FMNL1

  • Target Full Name

    Formin-like protein 1

  • Target Function

    May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.

  • Target Subcellular Location

    Cytoplasm. Cell membrane; Lipid-anchor. Cytoplasmic vesicle, phagosome.; [Isoform 3]: Cytoplasm, cell cortex. Cell projection, bleb. Note=Colocalized with F-actin in bleb protrusions.

  • Target Protein Families

    Formin homology family

  • Target Tissue Specificity

    Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

  • Target Synonyms

    8030453N10Rik; AI553564; C17orf1; C17orf1B; CLL associated antigen KW 13; CLL-associated antigen KW-13; FHOD4; FMNL; FMNL_HUMAN; Fmnl1; Fnrl; Formin like 1; Formin like; Formin related protein; Formin-like protein 1; Frls; KW 13; KW13; Leukocyte formin; MGC133052; MGC1894; MGC21878

  • Target Background

    This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined.

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