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The antibody against GLCE was raised in rabbit using the Recombinant Human D-glucuronyl C5-epimerase protein (29-617AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against GLCE was raised in rabbit using the Recombinant Human D-glucuronyl C5-epimerase protein (29-617AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human appendix tissue using GLCE Antibody at dilution of 1:1002
| Cat.No | ADC-49716A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GLCE |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human D-glucuronyl C5-epimerase protein (29-617AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O94923 |
Uniprot Id
O94923
Target Species
Human
Target Name
GLCE
Target Full Name
D-glucuronyl C5-epimerase
Target Function
Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
D-glucuronyl C5-epimerase family
Target Research Area
Cancer
Target Synonyms
GLCE; KIAA0836; D-glucuronyl C5-epimerase; EC 5.1.3.17; Heparan sulfate C5-epimerase; Hsepi; Heparin/heparan sulfate:glucuronic acid C5-epimerase; Heparosan-N-sulfate-glucuronate 5-epimerase
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