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Rabbit anti-Human GLRX5 Polyclonal Antibody

The antibody against GLRX5 was raised in rabbit using the Recombinant Human Glutaredoxin-related protein 5, mitochondrial protein (32-157AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-04819A

The antibody against GLRX5 was raised in rabbit using the Recombinant Human Glutaredoxin-related protein 5, mitochondrial protein (32-157AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-04819A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGLRX5
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Glutaredoxin-related protein 5, mitochondrial protein (32-157AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ86SX6
Background Information
  • Uniprot Id

    Q86SX6

  • Target Species

    Human

  • Target Name

    GLRX5

  • Target Full Name

    Glutaredoxin-related protein 5, mitochondrial

  • Target Function

    Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.

  • Target Involvement

    Anemia, sideroblastic, 3, pyridoxine-refractory (SIDBA3); Spasticity, childhood-onset, with hyperglycinemia (SPAHGC)

  • Target Subcellular Location

    Mitochondrion matrix.

  • Target Protein Families

    Glutaredoxin family, Monothiol subfamily

  • Target Synonyms

    C14orf87; Chromosome 14 open reading frame 87; FLB4739; GLRX 5; Glrx5; GLRX5_HUMAN; Glutaredoxin 5 homolog; Glutaredoxin related protein 5; Glutaredoxin-related protein 5; Glutaredoxin5; GRX5; MGC14129; mitochondrial; Monothiol glutaredoxin-5; PRO1238

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