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Rabbit anti-Human GMDS Polyclonal Antibody

The antibody against GMDS was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human GMDS (NP_001491.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-05292A

The antibody against GMDS was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human GMDS (NP_001491.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-05292A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGMDS
Target SynonymsGMD; SDR3E1; GMDSFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLaApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human GMDS (NP_001491.1).Target SpeciesHuman
Immunogen SequenceMAHAPARCPSARGSGDGEMGKPRNVALITGITGQDGSYLAEFLLEKGYEVHGIVRRSSSFNTGRIEHLYKNPQAHIEGNMKLHYGDLTDSTCLVKIINEVUniprot IDO60547
Background Information
  • Uniprot Id

    O60547

  • Target Species

    Human

  • Target Name

    GMDS

  • Target Full Name

    GDP-mannose 4,6 dehydratase

  • Target Function

    Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.

  • Target Protein Families

    NAD(P)-dependent epimerase/dehydratase family, GDP-mannose 4,6-dehydratase subfamily

  • Target Synonyms

    GDP D mannose dehydratase; GDP mannose 4 6 dehydratase; GDP-D-mannose dehydratase; GDP-mannose 4,6 dehydratase; GMD; Gmds; GMDS_HUMAN; OTTHUMP00000017756; OTTHUMP00000232770; SDR3E1; Short chain dehydrogenase/reductase family 3E member 1

  • Target Background

    GDP-mannose 4, 6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3, 5-epimerase, 4-reductase, designated FX in humans (MIM 137020).

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