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The antibody against GPM6A was raised in rabbit using the Fusion protein of Human GPM6A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against GPM6A was raised in rabbit using the Fusion protein of Human GPM6A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-30645A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPM6A |
| Target Synonyms | GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human GPM6A | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P51674 |
Uniprot Id
P51674
Target Species
Human
Target Name
GPM6A
Target Full Name
Neuronal membrane glycoprotein M6-a
Target Function
Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, growth cone. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, neuron projection.
Target Protein Families
Myelin proteolipid protein family
Target Synonyms
GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a
Target Background
Predicted to enable calcium channel activity. Involved in neuron migration and stem cell differentiation. Located in extracellular exosome.
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