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The antibody against GPR35 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GPR35. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
The antibody against GPR35 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GPR35. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
$167.00
| Cat.No | ADC-35531A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPR35 |
| Target Synonyms | GPR35; G-protein coupled receptor 35; Kynurenic acid receptor; KYNA receptor | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human GPR35. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HC97 |
Uniprot Id
Q9HC97
Target Species
Human
Target Name
GPR35
Target Full Name
G-protein coupled receptor 35
Target Function
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway. The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Note=Internalized to the cytoplasm after exposure to kynurenic acid.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Predominantly expressed in immune and gastrointestinal tissues.
Target Synonyms
GPR35; G-protein coupled receptor 35; Kynurenic acid receptor; KYNA receptor
Target Background
Enables C-X-C chemokine receptor activity. Involved in several processes, including chemokine-mediated signaling pathway; negative regulation of voltage-gated calcium channel activity; and positive regulation of cytosolic calcium ion concentration. Is integral component of plasma membrane.
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