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Rabbit anti-Human GPR55 Polyclonal Antibody

The antibody against GPR55 was raised in rabbit using the Peptide sequence from Human G-protein coupled receptor 55 protein (203-222AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-01310A

The antibody against GPR55 was raised in rabbit using the Peptide sequence from Human G-protein coupled receptor 55 protein (203-222AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-01310A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGPR55
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionPeptide sequence from Human G-protein coupled receptor 55 protein (203-222AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y2T6
Background Information
  • Uniprot Id

    Q9Y2T6

  • Target Species

    Human

  • Target Name

    GPR55

  • Target Full Name

    G-protein coupled receptor 55

  • Target Function

    May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. Expressed in osteoclasts and osteoblasts.

  • Target Synonyms

    LPIR1; GPR55

  • Target Background

    This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways.

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