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The antibody against HDAC11 was raised in rabbit using the Recombinant Human Histone deacetylase 11 protein (1-347AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against HDAC11 was raised in rabbit using the Recombinant Human Histone deacetylase 11 protein (1-347AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-40515A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HDAC11 |
| Target Synonyms | FLJ22237 antibody; HD 11 antibody; HD11 antibody; HDA11_HUMAN antibody; HDAC 11 antibody; HDAC11 antibody; Histone deacetylase 11 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Histone deacetylase 11 protein (1-347AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96DB2 |
Uniprot Id
Q96DB2
Target Species
Human
Target Name
HDAC11
Target Full Name
Histone deacetylase 11
Target Function
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
Target Subcellular Location
Nucleus. Note=Predominantly nuclear.
Target Protein Families
Histone deacetylase family
Target Tissue Specificity
Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
FLJ22237; HD 11; HD11; HDA11_HUMAN; HDAC 11; HDAC11; Histone deacetylase 11
Target Background
This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.
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