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The antibody against HIST1H2BN was raised in rabbit using the Recombinant Human Histone H2B type 1-N protein (2-126AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against HIST1H2BN was raised in rabbit using the Recombinant Human Histone H2B type 1-N protein (2-126AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human glioma using HIST1H2BN Antibody at dilution of 1:100
| Cat.No | ADC-40437A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HIST1H2BN |
| Target Synonyms | H2BC15 antibody; H2BFD antibody; HIST1H2BNHistone H2B type 1-N antibody; Histone H2B.d antibody; H2B/d antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Histone H2B type 1-N protein (2-126AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99877 |
Uniprot Id
Q99877
Target Species
Human
Target Name
H2BC15
Target Full Name
Histone H2B type 1-N
Target Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H2B family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
H2BC15; H2BFD; HIST1H2BNHistone H2B type 1-N; Histone H2B.d; H2B/d
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