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The antibody against HLCS was raised in rabbit using the Human HLCS as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against HLCS was raised in rabbit using the Human HLCS as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-53124A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HLCS |
| Target Synonyms | EC 6.3.4 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human HLCS | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P50747 |
Uniprot Id
P50747
Target Species
Human
Target Name
HLCS
Target Full Name
Biotin--protein ligase
Target Function
Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, and methylcrotonyl-CoA carboxylase.
Target Involvement
Holocarboxylase synthetase deficiency (HLCS deficiency)
Target Subcellular Location
Cytoplasm. Mitochondrion.
Target Protein Families
Biotin--protein ligase family
Target Tissue Specificity
Widely expressed. Mostly expressed in muscle, placenta and to a lower extent in the brain, kidney, pancreas, liver and lung.
Target Synonyms
Biotin [acetyl CoA carboxylase] ligase; Biotin [methylcrotonoyl CoA carboxylase] ligase; Biotin [methylmalonyl CoA carboxytransferase] ligase; Biotin [propionyl CoA carboxylase [ATP hydrolyzing]] ligase; Biotin apo protein ligase; Biotin apo-protein ligase; Biotin protein ligase; Biotin--[acetyl-CoA-carboxylase] ligase; BPL1_HUMAN; HCS; HLCS; Holocarboxylase synthetase; Holocarboxylase synthetase, EC 6.3.4
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