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The antibody against HS3ST1 was raised in rabbit using the Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 1 protein (21-307AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against HS3ST1 was raised in rabbit using the Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 1 protein (21-307AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human heart tissue using HS3ST1 Antibody at dilution of 1:100
| Cat.No | ADC-21992A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HS3ST1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 1 protein (21-307AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O14792 |
Uniprot Id
O14792
Target Species
Human
Target Name
HS3ST1
Target Full Name
Heparan sulfate glucosamine 3-O-sulfotransferase 1
Target Function
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site.
Target Subcellular Location
Golgi apparatus lumen.
Target Protein Families
Sulfotransferase 1 family
Target Tissue Specificity
Highly expressed in the brain and kidney and weakly expressed in the heart, lung and placenta.
Target Synonyms
3-OST-1; 3OST; 3OST1; EC 2.8.2.23 ; h3 OST 1; h3-OST-1; Heparan sulfate (glucosamine) 3 O sulfotransferase 1; Heparan sulfate 3 O sulfotransferase 1; Heparan sulfate 3-O-sulfotransferase 1; Heparan sulfate D glucosaminyl 3 O sulfotransferase 1; Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1; Heparan sulfate glucosamine 3-O-sulfotransferase 1; Heparin glucosamine 3 O sulfotransferase; HS3S1_HUMAN; HS3ST 1; Hs3st1
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