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The antibody against IFNL2 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human IL-28. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against IFNL2 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human IL-28. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of MCF7 cells using IL-28 Polyclonal Antibody
| Cat.No | ADC-37048A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IFNL2 |
| Target Synonyms | lambda 2) antibody; Interleukin 28A antibody; Interleukin-28A antibody; ZCYTO20 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human IL-28. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IZJ0 |
Uniprot Id
Q8IZJ0
Target Species
Human
Target Name
IFNL2
Target Full Name
Interferon lambda-2
Target Function
Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Target Subcellular Location
Secreted.
Target Protein Families
Lambda interferon family
Target Synonyms
Cytokine ZCYTO20; IFN-lambda-2; IFNL2; IL-28A; IL28A; IL28A_HUMAN; Interferon lambda 2; Interferon lambda-2; interleukin 28A (interferon, lambda 2); Interleukin 28A; Interleukin-28A; ZCYTO20
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