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The antibody against IKZF4 was raised in rabbit using the Synthetic peptide of Human IKZF4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against IKZF4 was raised in rabbit using the Synthetic peptide of Human IKZF4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-25424A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IKZF4 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human IKZF4 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H2S9 |
Uniprot Id
Q9H2S9
Target Species
Human
Target Name
IKZF4
Target Full Name
Zinc finger protein Eos
Target Function
DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1.
Target Subcellular Location
Nucleus.
Target Protein Families
Ikaros C2H2-type zinc-finger protein family
Target Tissue Specificity
Highly expressed in skeletal muscle, low levels of expression in heart, thymus, kidney, liver, and spleen. Expressed in the hematopoietic cell lines MOLT-4, NALM-6 and K-562. Highly expressed in THP-1 and M-07e cell lines, which have characteristics of my
Target Synonyms
EOS; Eos protein; IKAROS family zinc finger 4 (Eos) ; IKAROS family zinc finger 4; Ikaros family zinc finger protein 4; IKZF4; IKZF4_HUMAN; KIAA1782; Zinc finger protein Eos (IKAROS family zinc finger protein 4); Zinc finger protein Eos; Zinc finger protein; subfamily 1A; 4 (Eos); Zinc finger protein; subfamily 1A; member 4; Zinc finger transcription factor Eos; ZNFN1A4
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